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A baby breaks a record at birth from a 27-year-old frozen embryo

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Success opens the door to confirm that it is possible to preserve fertilized embryos “indefinitely”

A couple from Tennessee ( United States ) has broken a record by giving birth to a baby from a frozen embryo 27 years ago, which shows that fertilized embryos could be kept “indefinitely,” a spokesperson for the center told Efe on Friday. fertilization that carried out the process.

Tina and Ben Gibson have broken their own record with the birth of Molly since they already have another daughter who was conceived from a brother embryo that was frozen for 24 years.

The insemination of this donated embryo was carried out by the National Embryo Donation Center (NEDC), a fertility center with a religious focus, according to the organization itself.

“Molly Everette Gibson spent more than 27 years as a frozen and preserved embryo, marking the only known record for the longest frozen embryo leading to birth,” it said in the statement.

Mark Mellinger, the spokesman for the NEDC, told Efe on Friday that this confirms that “as long as the embryos are frozen and properly stored, we believe that they can remain ‘in good condition’ indefinitely .”

The NEDC focuses on saving fertilized embryos that are going to be discarded for donation to couples with fertility problems.

Molly’s embryo was frozen in 1992 and could have been born at any time in the last 27 years.

It is the genetic sister of the previous one, which comes from an embryo frozen at the same time and which was born after 24 years in conservation, which also shows that the equipment used in the 90s was advanced enough to guarantee the safety of the process.

Fertilized embryos are implanted in the mother’s uterus and are one of the cheapest alternatives for couples with fertility problems.

“This is proof that no embryo should be discarded and not considered ‘old’, ” said NEDC Director Jeffrey Keenan.

Five appliances you didn’t know you cleaned badly

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If we use the correct method we will be able to eliminate the dirt in an effective way

The coronavirus crisis has forced the Spanish population to stay in their homes for a long time without being able to leave. During this long period of time, many have come close to consuming the entire Netflix catalog or some other platform. And it is that, without the possibility of going out to the street, the forms of entertainment are reduced. So much so that some have chosen to follow all the viral challenges that spread like wildfire on social networks.

Others, on the other hand, have racked their brains to try to take advantage of some way while it vanished without doing anything productive. Thus, one of the activities that have been repeated the most during these months has been to carry out general cleaning of the house. During confinement, countless cabinets, beds, sofas, and electrical appliances have been moved to catch every last spot or speck of dust. The houses of many have looked like new.

However, some devices have been able to with our patience. And it is that, sometimes, no matter how much we clean something, it is impossible to remove the dirt. Cleaning grease from the oven or microwave seems like an impossible thing that only those who have the best cleaning products can achieve.

But, not obtaining the desired results, in these cases, is usually due to not using the proper technique. Therefore, in this article, we point out some tricks to effectively clean those devices that you have been cleaning badly all your life.

Microwave

The days of scrubbing the grease out of this small appliance with all your might are over. Fill a bowl with water and vinegar and microwave it for a couple of minutes. The steam that will be created will make the dirt loosen easily and you can remove it with a cloth.

The oven and its trays

To clean the oven with ease, choose to create a paste based on baking soda and water, spread it inside, and leave it to act overnight. The next morning, wipe off the mixture with a cloth, spray the inside of the oven with a little vinegar, and turn it on for a few minutes to dry.

To clean the trays of this appliance we can mix hydrogen peroxide with sodium bicarbonate. Then we will rub this mixture and let it act for about an hour. Then we will remove the liquid with a cloth.
Coffeemaker
If your coffee starts to taste a little strange, before changing your coffee maker, try to clean it properly. Fill half the tank with water and the other half with vinegar and put it to work without coffee.

The food cutting board

The eaten cutting board is an everyday object that is of great help to us, but over time it accumulates a large amount of dirt and bacteria that are often difficult to remove. And, with a scouring pad, we can spend a lot of time to reach the most impenetrable corners. To fix this problem, we can rub half a lemon with a little coarse salt against the board. Then we must wash it with a little wheal and water so that it remains unpolluted.

Toothbrushes

It is important to start by remembering the importance of changing your toothbrush at least once every three months. Despite what many people believe, it is not enough to run the brush through the water to clean it. If we want to avoid dental problems, try putting the brush in a glass with white vinegar for several hours. Then you just have to rinse it well to enjoy a clean, bacteria-free toothbrush again.

What is norovirus? A new virus threatens China

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An outbreak in a school in Sichuan has warned of the presence of new highly contagious diseases in the Asian country

While Europe continues to fight against covid-19, in China they already have a new enemy: norovirus. An outbreak affecting 50 students at a school in Sichuan province has been detected.

What is norovirus and what symptoms does it have?


According to the CDC (Centers for Disease Control and Prevention) of the US, noroviruses are a highly contagious virus, which often has outbreaks between November and April, which cause gastroenteritis and whose main symptoms are vomiting, diarrhea, nausea, and stomachache.

How is it spread?


This virus passes from one person to another through contaminated food and it does so very efficiently and quickly.

What risks does it have?


It is not a virus, a priori, serious and the symptoms last a few days. As with covid-19, it can be worrisome in the case of the elderly and very young children. The greatest risk is severe dehydration.

How to avoid infections?


Habits acquired with the coronavirus, such as frequent hand washing, are also useful to protect against norovirus. In addition, it is recommended to wash fresh food thoroughly, cook seafood thoroughly, and stay home while symptoms last.

 

The risks of installing a portable pool on the terrace or roof

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The surveyors advise not to exceed 30 centimeters in-depth and take into account the slab and the year of construction of the house

Temperatures rise, summer is approaching and the forced confinement that we have experienced due to the coronavirus is coming to an end. Three factors that will surely multiply, together with the economic crisis, the presence of portable swimming pools in a good number of Spanish homes. Rising temperatures and the economic crisis accentuate this dangerous trend.

But is it advisable? How safe is this growing trend? Where to install the pool? What dimensions should it have? What factors should we take into consideration?

Be careful, because it is not a matter to be taken lightly. The consequences can be unpredictable, especially if the intention is to install the inflatable pool on some floor of a building, and especially on terraces and balconies, according to the Madrid Surveyors Association.

The specialists of the Technical Cabinet of this institution insist that the characteristics of the slab that will support the weight of the pool with bathers inside must be taken into account. ” The slab, as a structural element, is designed for certain overloads of use. For example, to hold shelves, furniture, beds, meetings for a meal and similar examples,” says David Arias Arranz, member of the Technological Advisory of the College of Madrid Surveyors.

This admitted overload depends largely on two factors: the year of construction of the building and the type of slab structure. The older it is, the greater the limitation, taking into account that the calculation of the overload of the applicable regulations of the time, in very old buildings, could not even have been taken into account. In these cases, the risk may be higher and the need for analysis high.

According to David Arias, “the type of structure that makes up the floor is another fundamental element since its resistance to overload varies enormously. A wooden floor is not the same as a concrete one, a steel one or a mixed one”. Furthermore, according to this expert, “it is important to know the structural state of the building in case it had any previous pathology, such as injuries, cracks, reinforcements or rusted steel beams.

Taking into account all these factors, caution and common sense advise, according to the Association of Surveyors, that the overload of the slab ranges between 200 and 300 (at most) kilos per square meter. Therefore, the depth (height of the water surface) should not exceed 20-30 centimeters in use in building floors and terraces, something important to take into account because the volume and weights are very different depending on the number and characteristics (children, adults …) of the bathers in the pool.
And the location? According to David Arias Arranz, “the edge areas of swimming pools are the most unfavorable. You should try to place them in the areas where the beam and the column meet. Let’s imagine a trampoline: if I stand on the edge (as if I were going to jump) it curves (It bends). On the other hand, when I am at the beginning of it (embedment) it does not deform at all “.

If the pool is to be installed on a low floor, in contact with the ground, “we can be calmer,” indicates this rigger, “since its characteristic resistance (what it holds) is perfectly acceptable for any seasonal or temporary pool (the typical removable seasonal ones), being able to reach 60, 70 and up to 80 centimeters in height without a problem “.

In any case, the College of Surveyors of Madrid recommends having a technical architect to analyze and evaluate all these parameters, because in extreme cases we could witness an unforeseen misfortune.

The plants that last the longest without watering

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Choosing the right type helps fill the house with life with less effort to care for them

Taking care of plants is one of the most pleasant tasks in the home. However, on many occasions, due to lack of time, we cannot dedicate all the care they need. Therefore, if you are a plant lover, but do not have much time to care for them, do not despair. There are a number of the most resistant types of plants that practically do not need water to survive.

Forget those withered or yellowed plants and fill your home with the most intense green, fleeing from the efforts in their care. Sign up for the following types of plants and you will discover all the advantages of the most resistant plants.

Photos

These plants adapt very well to all types of light in homes, whether direct, indirect, natural, or artificial. In addition, its large leaves make it the most beautiful. Of course, its main advantage is that it needs very little water to look splendid. It acclimates perfectly to the most adverse conditions, so you only have to give it away when you see that its soil is dry.

Ribbons

Ribbons are one of the queens in indoor plants. They are one of the best sellers due to their high capacity to acclimatize to various conditions. It needs very little water, especially in winter, since half a cup a week will be enough. In summer it will not require too much attention because with a weekly glass of water it will nourish itself enough to look perfect.

Tiger tongue

These plants are real warriors in terms of their resistance to lack of light and lack of water. Therefore, it can survive practically without care. In fact, its main enemy is excess water.

Aloe vera

In addition to its well-known healing powers, aloe vera is a most grateful plant. It does not need practically any care. Its irrigation can be extended, even, every two weeks.

The best ceiling fans

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With the arrival of heat, a fan can be your best ally and also a decorative element

Summer has come to stay with us for the next three months and the high temperatures will gain prominence in the thermometers.

For this reason, Spanish homes are looking for remedies to try to make the heat press as little as possible. And although the most used are air conditioning systems, we cannot forget the traditional fans.

If you want to use one of these, in addition to moving the air and freshening up your room, as a decorative element, don’t think twice and observe these shopping tips on which to choose.

Westinghouse Industrial

It is a cheap option and highly valued by users since it is very versatile when it comes to being installed on different types of ceilings.

If we are looking for a fan with large blades, without lighting, and with wall control, this is our option!

This fan has a diameter of 142cm, so it is recommended for fairly large rooms that measure between 20 or 30m2.

Cecotec ForceSilence 3 blades

Cecotec has one of the best-selling options. This model, with 3 blades, has a modern but simple design. Its 106cm diameter makes it perfect for rooms up to 13m2.
It has a lamp that illuminates remarkably. We can use it as the main and only lighting for the room. Of course, it does not include the bulb with the purchase so we will have to buy it separately.

Despite having only 3 blades, the aerodynamic design makes it move the air efficiently. Bastilipo: Quality of materials, functionality, and design

It is one of the most traditional options with the best design: made of wood and with 4 rounded blades. It has a diameter of 105cm, perfect for rooms up to 13m2.

The manufacturing material is metal, with an aged bronze design and walnut-colored blades, with leather finishes. The metal material ensures a long life for our new fan and easy maintenance.

It is controlled via the remote control and has 3 speeds, all extremely quiet thanks to its stable and robust design. It also has the inverse function, to give a cold breeze in summer and distribute warm air in winter.

Orbegozo CP-15075 N: For small rooms

Orbegozo stands out with this option designed in wood with 6 blades and 80cm in diameter, which allows large amounts of air to be moved in the smallest rooms. Aesthetically it is one of the most elegant options.

This option includes a lamp. The bulbs are not included, but the E14 60W type can be used. It is not much, so even though it has a lamp, if the room is not very small we may need some other alternative lighting.

It is very quiet at the three speeds available. And it won’t vibrate at all even at the highest speeds, so it can be worn at night in comfort.

Faro Barcelona de TONSAY: In medium rooms

If our room measures more than 18m2, this option may interest us. It is a 132cm diameter fan, 3 wooden blades, and a motor made of steel.

The quality of the materials is indisputable. In addition, the blades are reversible: on one side it has a white finish and on the other a maple finish. In this way, we can choose the color that best matches the rest of the room.

The lamp has space for 2 low consumption E27 type bulbs (15W). This lamp, although it gives enough light, if the space is too large we may want to add alternative lighting to the room.

 

BMS bets on science to transform the patient’s life

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Bristol-Myers Squibb continues to pursue innovation in drug development in fields such as oncology, hematology, immunology and cardiovascular disease

Bristol-Myers Squibb (BMS) and Celgene joined a year ago in what would be one of the most important operations in the pharmaceutical sector in recent times . The size acquired by the company places it as the 5th company on a global scale and this allows it to confront solvency a scenario of investment and development of new drugs for the long term and to respond to the needs of new treatments of patients.

The new company brings together the best of a biotech and a large pharmaceutical company, enabling them to develop innovative drugs for patients with cancer and other serious diseases. BMS is aware that this new dimension comes with an even greater responsibility to its thousands of patients. Therefore, the company aims to advance science from its leading franchises in oncology, hematology, immunology, and cardiovascular disease, and thanks to one of the most diverse and promising ‘pipelines’ in the industry.

The BMS team – currently made up of 30,000 employees worldwide, of which about 400 are in Spain and Portugal – works every day to discover, develop and provide innovative medicines that help them overcome serious pathologies and achieve a better quality of life .

A history of scientific excellence

BMS has pioneered the development of immunotherapy, a new class of drugs that stimulate the immune system against cancer. The company has also changed the treatment of diseases such as multiple myeloma and serious tumors, such as metastatic melanoma or lung cancer, increasing the life expectancy of its patients.

In addition, the company is moving toward the next generation of therapeutic options, such as CAR-T, and continues to seek cutting-edge, life-changing treatments such as cell therapy.

The leader in innovation in Spain

Although the two legal entities still coexist in Spain at the moment, thanks to the union, BMS has positioned itself as the second company in the number of clinical trials underway in our country. Specifically, it has more than 200, for which the company has allocated approximately 50 million euros.

Likewise, BMS has a leading research center in Seville, the Translational Research Center (CITRE), which has become the European benchmark in translational cancer medicine.

With more than 50 molecules in various stages of development, the company’s investment in research and development currently exceeds $ 6 billion worldwide.

Commitment to equality and diversity

Bristol Myers Squibb is committed to generating quality, diverse, and inclusive jobs. 61% of its 400 employees are women and the company’s governing body in the country is more than equal. Proof of this is that the Ministry of Equality has recently awarded BMS the “Equality in the Company” distinction, a certificate awarded for excellence in the application and development of equality measures between women and men and in the development of plans and policies. equality in the company to those companies that achieve results in the implementation of these measures.

Close to society

The mission and commitment of BMS are now more important than ever, in the context of uncertainty caused by the pandemic. Thus, although several months have passed since the start of the health crisis, the world continues to face a unique challenge for humanity and science.

As a company concerned with helping society and reducing inequalities, BMS decided to support the most vulnerable groups: health professionals, families with minors at risk of exclusion, or the elderly. Save the Children, Unicef, Cáritas, the Red Cross and the Food Bank are some of the institutions through which we have channeled this aid.

Tricks to clean the plastic pool in your house

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Mold and algae tend to accumulate and bacteria that are harmful to health can appear

The plastic pools removable are ideal to beat the heat of summer. They are enjoyed by children and also by the elderly. However, many do not usually have filters or purifiers, so dirt tends to accumulate easily and bacteria that are harmful to health can appear. Therefore, it is advisable to clean them frequently.

It is enough to have a disinfectant par excellence on hands such as white vinegar, bleach, clean water, and dish soap. These are the simple steps to get your pool ready:

First of all, the dirty water must be emptied from the inflatable pool and immediately afterward to start cleaning it. It is best to do it quickly to prevent more algae or mold from appearing. The more time that passes, the more all that dirt will adhere to the surface and the more it will cost to remove.

Just fill a container with water and a few drops of white vinegar. With a cloth, proceed to clean the entire pool, especially rubbing the areas where there is more accumulated dirt. An alternative to white vinegar is dishwasher soap, especially because the smell it gives off is more pleasant.

In addition to the usual clothes, root brushes can always be used with care not to damage the plastic and avoid the dreaded punctures or tears.

If the pool has not been cleaned in a long time and a lot of dirt has accumulated, a mixture of water and bleach should be used. More specifically, dilute one part of bleach in three parts of water and proceed to clean the walls and the bottom of the pool with a cloth. Apart from these home remedies, you can also opt for special products such as anti-algae.

Once the cleaning of the entire pool is finished, it is important to rinse it well with plenty of water to remove all the remains of the mixture that has been used. It is best to do it with a pressure hose. In any case, it should be clarified several times.
In addition, it is recommended to have a filter to avoid having to change the water constantly. This system, which usually has sand, will help eliminate the dirt that remains at the bottom of the pool.

Other products that help make the water transparent are chlorine – liquid, in tablets or powder -, salt to disinfect the water and active oxygen , which acts on the organic remains of the water. The latter is also found in both pills and liquid.

Once the summer is over and it is time to collect the pool for good until next year, it is always better to keep it clean and dry.

The trends that will cause a sensation for the kitchen

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The design of these spaces tends to be more electric and practical and moves away from minimalism

The kitchen design garnishes and this year tends to be more eclectic and practical favoring customizing spaces according to the tastes and needs. Comfortable kitchens in which design is at the service of home design. Many kitchens are integrated into the living rooms and become one of the most used spaces in the house.

Practical kitchens whose design must take into account the available space but also with the needs of each family. Kitchens are prepared for their main mission, which is always to make food but also to bring the whole family together around a table for breakfast, lunch, or dinner. We are going to talk about five trends for 2020 that are being imposed in designer kitchens that will surely surprise you.

Forget the shooters

This year the classic handles on the doors of cabinets and drawers disappear. Nothing modern or vintage handles like in other seasons. Most of the electrical appliances incorporate a handle on their doors and we can also find integrated handles on the sides or in the upper band of doors and drawers. The reason for this elimination or integration of the handles is that the kitchen furniture is intended to resemble those in the living room. A trend that comes when opening the kitchens and eliminating partitions by adding the kitchen to other spaces in the house such as the living room.

Black furniture

The latest trend in design is kitchen furniture in black. A very original piece of furniture that is usually combined with golden taps, betting on style and elegance. Also for those who are not comfortable with a total black kitchen, you can add black details such as the countertop and leave gold for the taps and lamps. Even the combination of furniture in white or light tones with black details is always in fashion.

Diversity in lamps

Another novelty is that kitchen lamps of all styles are brought from the most modern and innovative to those that provide a vintage touch. The kitchens this 2020 surprise with all kinds of lamps from the hanging ceiling to the most varied wall lights. The important thing is that the light illuminates areas such as the dining table or the worktop that need extra lighting to be able to work in the kitchen.

Bet on wood

Wood is a classic material that triumphs in the design of kitchens every year. It can be applied to floors, walls, countertops, and even kitchen furniture. The natural and sustainable are one of the trends in the decoration of this 2020 for any home. It’s even a good idea to add recycled or reclaimed wooden furniture from Grandma’s storage room like tables or chairs. Kitchenware and kitchen utensils made with natural, ecological, and sustainable materials are also carried for all types of kitchens.

Out minimalism

If a few years ago the trend was to hide all the objects in the kitchen inside the cabinets, it is again taken that the objects are in sight. Add shelves or shelves and furniture with glass doors to place the jars of vegetables, pasta or rice and all kinds of utensils. Apothecary furniture is also carried in the dining rooms where the crockery or glassware can be seen. Do not hide what you need to have on hand in the cupboards and enjoy a comfortable and practical kitchen.
The design of modern kitchens must take into account the latest trends but also the needs of each family. Different kitchens that prioritize comfort and that usually have a space for a simple dining room.

Spain performs its first uterus transplant from a living donor

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The Clinic of Barcelona has carried out the transplant of this organ between two sisters

The Hospital Clínic de Barcelona has carried out the first uterus transplant in Spain from a living donor, who has donated it to her sister, who was born without this organ, which is known as Rokitansky syndrome, this center reported this Thursday doctor in a statement.

The transplant was carried out on October 5, led by the heads of the Gynecology services of the Hospital Clinic, Francesc Carmona, and of Urology and Renal Transplantation, Antonio Alcaraz.

The process that has led to this pioneering intervention began five years ago and is part of the research project “Feasibility study of a living donor uterine transplant procedure with obtaining a graft for robotic surgery”, to validate the viability of this surgery.

The main requirement to be a candidate for this type of operation is to suffer from Rokitansky syndrome, which is a congenital disorder of the female reproductive system that affects one in every 5,000 women in the world.

These women are born without a uterus and fallopian tubes and, in the specific case of the transplant recipient, she was the only compatible candidate out of 30 who presented for a transplant.

The Clinic has reported today that uterus transplantation is a highly complex process that is divided into two phases: the removal of the organ carried out by robotic surgery, to be as less invasive as possible, and its implantation, which required open surgery.

The duration of the operation was about twelve hours, in terms of extraction, and another four for implantation.
A multidisciplinary team of more than 20 people performed the transplant, including gynecologists, transplant surgeons, gynecology and transplant nurses, anesthetists, and nursing assistants.

Dr. Antonio Alcaraz explained that the uterus “is a complex organ, with poor vascularization of the arteries and a large network of veins, of which the largest must be sought to drain the blood that reaches the uterus.”

Added to these difficulties is the subsequent process that focuses on the recipient since, according to Dr. Carmona, the success of everything “is determined by the viability of the organ, that it functions and that the woman becomes pregnant.”

The health evolution of the woman receiving her sister’s uterus, two months after the operation, is good and she has already had her first menstrual cycle, the same sources have reported.

At this point in the process, the woman is expected to be implanted with an embryo of the eleven previously fertilized in vitro, so that she can become pregnant.

In the event that she becomes pregnant, immunosuppressive drugs will be maintained – to prevent her immune system from damaging the transplanted organ – until a second pregnancy.

Once her wish to be a mother is complete, the donated uterus will be removed by laparoscopy after the second delivery, provided that this is her gestational wish.

This has been the first uterus transplant performed in Spain, but not in Europe, since the first birth after another transplant from a living donor took place in Sweden in 2014, specifically at the University Hospital of Sahlgrenska, of the University from Gothenburg, and was led by Dr. Mats Brännström.

To date, 70 uterus transplants have been performed around the world, from which around twenty babies have been born.